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Friday, August 7, 2020 | History

3 edition of Effect of microgravity on epidermal development in the rat found in the catalog.

Effect of microgravity on epidermal development in the rat

Effect of microgravity on epidermal development in the rat

final report

  • 105 Want to read
  • 39 Currently reading

Published by National Aeronautics and Space Administration, National Technical Information Service, distributor in [Washington, DC, Springfield, Va .
Written in English

    Subjects:
  • Aerospace medicine.,
  • Calcium.,
  • Differentiation (Biology),
  • Epidermis.,
  • Fetuses.,
  • Microgravity.,
  • Morphology.,
  • Physiological responses.,
  • Rats.,
  • Transport properties.

  • Edition Notes

    StatementSteven B. Hoath.
    SeriesNASA contractor report -- NASA CR-200130.
    ContributionsUnited States. National Aeronautics and Space Administration.
    The Physical Object
    FormatMicroform
    Pagination1 v.
    ID Numbers
    Open LibraryOL15424762M

      We are interested in studying the effects of simulated microgravity on the survival and self-renewal of NCSCs. NCSCs extracted from the hair follicle bulge region of the rat whisker pad were cultured in vitro, respectively, in a 2D adherent environment and a 3D suspension environment using the rotatory cell culture system (RCCS) to simulate. Audio Books & Poetry Community Audio Computers, Technology and Science Music, Arts & Culture News & Public Affairs Non-English Audio Spirituality & Religion Librivox Free Audiobook YouTube Power Hour Podcast: YouTube, YouTube Channel, Video Marketing, YouTuber, IGTV, Erika Vieira, Video, Instagram Overeaters Anonymous ElectraTone Guitar Effects.

    The effects of microgravity on muscle tissues If you're seeing this message, it means we're having trouble loading external resources on our website. If you're behind a web filter, please make sure that the domains * and * are unblocked. effects of microgravity on the human body, became a key priority. The Immunology Laboratory at the NASA Johnson Space Center investigates the effects of spaceflight on various aspects of human physiology. One of the primary areas of research conducted by the Immunology Laboratory is the effect Microgravity Effects on Human Physiology.

      Here we report the results of two space flight missions examining the effect of removing gravity on the development of surface righting. Since the essential stimulus that drives this synergy, gravitation, was missing, righting did not occur while the animals were in the microgravity environment. Effect of Microgravity on Bones: Challenges to Addressing Risks to Human Health & Performance Endocrine Grand Rounds McGuire Veterans Affairs Medical Center Jean D. Sibonga, Ph.D. Lead, Bone Discipline Human Research Program [HRP] Johnson Space Center, Houston, TX National Aeronautics and Space Administration


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Effect of microgravity on epidermal development in the rat Download PDF EPUB FB2

Get this from a library. Effect of microgravity on epidermal development in the rat: final report. [Steven B Hoath; United States. National Aeronautics and Space Administration.]. nections with sensory neuron dendrites. An effect of microgravity on synaptic development in the gravistatic maculae remains to be determined.

Role of gravity on development of vestibular connections To study the effects of gravity on the formation of connections between gravity receptors of the inner ear and brain, pregnant rats were launched aboard the.

+ Effect of Microgravity on Epidermal Development in the Rat () Experiment Performed on: + STS Role: ARC Payload Scientist Degree: Not available. To evaluate the effects of epidermal growth factor (EGF) in dietary milk, a new method of delivering an artificial (EGF-deficient) formula was developed using 42 rat pups, 1–14 days of by: Braz J Med Biol Res, DecemberVolume 44(12) The effect of microgravity on tissue structure and function of rat testis.

Ye Ding 1 *, Jin Tang 2 *, Jun Zou 2, Ruiping She 1, Yinghua Wang 1, Zhuo Yue 1, Jijing Tian 1, Kangkang Xia 1, Jun Yin 1 and Desheng Wang 3.

1 Department of Veterinary Pathology, Key Laboratory of Zoonosis of Ministry of Agriculture, 2 National Animal. Moreover, investigating the effects of microgravity and PRP on an in vitro wound healing model, it was found that PRP is able to counteract the microgravity-induced impairment in fibroblast.

A spaceflight has enormous influence on the health of space voyagers due to the combined effects of microgravity and cosmic radiation. Known effects of microgravity (μ g) on cells are changes in differentiation and growth. Considering the commercialization of spaceflight, future space exploration, and long‐term manned flights, research focusing on differentiation and growth of stem.

The overall goal of this project was to investigate the effects of prolonged weightlessness on the development of the skin in the fetal and newborn rat. Microgravity induces a number of significant physiological changes in the cardiovascular, nervous, immune systems, as well as the bone tissue of astronauts.

Changes in cell adhesion properties are one aspect affected during long-term spaceflights in mammalian cells. Cellular adhesion behaviors can be divided into cell–cell and cell–matrix adhesion.

Reduced secretion of OPG by osteoblast cells due to the effect of microgravity, more RANKL are available to attach to RANK receptor on pre-osteoclast, more activation of osteoclast and more bone resorption. Microgravity effects on mesenchymal stem cells which decreases the number of.

Microgravity affects muscles mass and physical performance in humans and animals. 24 In general, slow type contractile proteins were found to be reduced in microgravity.

This appears to be a specific effect of microgravity. The shorter 13 d and 15 d flights on the space shuttle, however, did not cause increased expression of these proteins in female glands. This suggests that longer exposure to microgravity may result in more profound changes.

Toggle navigation Life Sciences Data Archive. HOME ; FOR RESEARCHERS ; FOR EDUCATORS; FOR STUDENTS; FOR EVERYONE; Search By: Experiment; Mission ; Personnel. Vol Issue 3, March ISSN: (Print) X (Online) Simulated microgravity significantly altered metabolism in epidermal stem cells.

Bin-Bin Li Springer for Research & Development Support. The effect of culturing a living skin equivalent (LSE) in a submerged microgravity environment was investigated. LSEs were developed by culturing normal human epidermal keratinocyte (NHEK) on a submerged fibroblast and type 1 collagen gel matrix.

tail-suspension model to simulate microgravity, and investigated the effect of microgravity on the tissue structure and function of the testis in sexually mature male rats. Forty-eight male Wistar rats weighing g were randomly assigned to three groups (N.

Author(s): Hoath,Steven B; United States. National Aeronautics and Space Administration. Investigator(s): Hoath,Steven B; Non-NASA Center: U Cincinnati Coll Med, OH. Shing-Chen Lin, Guo-Hau Gou, Ching-Wu Hsia, Cheng-Wen Ho, Kun-Lun Huang, Yung-Fu Wu, Shih-Yu Lee and Yi-Hui Chen, Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells Via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling, Stem Cells and Development, /scd A new study by NASA intends to examine the detrimental effects of microgravity on the immune system, by studying the blood of rats and blue mussels over the course of a prolonged stay aboard the.

To address this hypothesis, we investigated the effects of microgravity on early lineage commitment of mouse embryonic stem cells (mESCs) using the embryoid body (EB) model of tissue differentiation.

We found that exposure to microgravity for 15 days inhibits mESC differentiation and expression of terminal germ layer lineage markers in EBs. Part of the Research for Development book series (REDE) Abstract.

On April 6,the SJ recoverable microgravity experimental satellite (SJ satellite) was launched from Jiuquan in China, which conducted a mission of space microgravity experiments. Epidermal growth factor. EGFR.

Epidermal growth factor receptor. ESCs. Embryonic stem.Effects of Microgravity on the Immune System Effects of Microgravity on the Immune System. Changes in resistance to bacterial and viral infections in Apollo crew members has stimulated interest in the study of immunity and space flight.

Results of studies from several laboratories in both humans and rodents have indicated alterations after space flight that include the following .The effects of microgravity on the Human Body. Many Sci fi books and films have artificial gravity for example in Enders Game the school had an artificial gravity field and zero gravity in the battle room.

Sci fi can manipulate gravity, however presently we have not managed to create artificial gravity and because of this, humans have many.